The assistant can work autonomously for a very long time. The only thing that breaks the run is when it needs to stop and ask you for something.
Before I send a big task, I prepare everything it might need up front: the business name and details, brand colors, the copy or the instruction "write it yourself in this voice," folder paths, and example links for the style I want. Every question the assistant doesn't need to ask me is twenty minutes it can spend building instead of waiting.
My rule: if I'd hand this to a human contractor on day one, it goes in the prompt.